Colchicine is a medication that can be taken to treat gout symptoms during a gout flare up. Colchicine tablets are commonly used if you can’t take over the counter painkillers like ibuprofen, or if these painkillers fail to effectively relieve the symptoms.
Colchicine can be taken regularly to help avoid gout attacks, or as soon as a gout attack occurs to help treat your symptoms but it is not to be taken for more than 5 days consecutively.
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Do not take Colchicine Tablets:
• if you are allergic to colchicine or any of the other ingredients of this medicine (listed in section 6)
• if you have a severe blood disorder
• if you are pregnant
• if you are breastfeeding
• if you are a woman of childbearing age, unless you are using effective contraception
• if you have severe kidney or liver problems
• if you are undergoing haemodialysis
• if you have kidney or liver problems and you are taking certain medicines (see ‘Other medicines and Colchicine Tablets’) If you are not sure whether any of the above apply to you, talk to your doctor or pharmacist before
Warnings and precautions:
Talk to your doctor or pharmacist before taking Colchicine Tablets if you:
• have problems with your heart, kidneys, liver or digestive system
• are elderly and weak
• have a blood disorder Colchicine Tablets can be toxic so it is important that you do not exceed the dose prescribed by your doctor.
There is only a slight difference between an effective dose of Colchicine Tablets and an overdose. Therefore, if you get symptoms such as nausea (feeling sick), vomiting (being sick), stomach pain and diarrhoea, stop taking Colchicine Tablets and immediately contact your doctor (see also section 4 ‘Possible side effects’). Colchicine Tablets can cause a serious decrease in bone marrow function leading to a decrease in certain white blood cells (agranulocytosis), a decrease in red blood cells and pigment (aplastic anaemia) and/or a low blood platelet count (thrombocytopenia).
You should have regular blood tests to monitor any changes. If you develop symptoms such as fever, inflammation of the mouth, sore throat, prolonged bleeding, bruising or skin problems, stop taking this medicine and contact your doctor immediately. These could be signs that you have a serious blood problem and your doctor may want you to have a blood test.
What are the uses for Colchicine?
Colchicine is used for the treatment of acute flares of gout. It also is used for treating FMF in adults and children 4 years of age or older. Other unapproved uses of colchicine include treatment of pseudogout, amyloidosis, and scleroderma. These unapproved uses of colchicine require further evaluation.
What brand names are available for Colchicine? Colcrys, Mitigare
Is Colchicine available as a generic drug?
Do I need a prescription for Colchicine?
What are the side effects of colchicine?
The most common side effects of colchicine are dose-related and include: nausea, vomiting, abdominal pain, and diarrhea. Colchicine also may cause hair loss, weakness, and nerve irritation.
What is the dosage for Colchicine?
The recommended dose of colchicine for acute gout is 1.2 mg at the first sign of symptoms followed by 0.6 mg one hour later. The maximum dose over a one hour period is 1.8 mg. In clinical trials, 1.8 mg of colchicine administered over 1 hour was as effective as 4.8 mg administered over 6 hours, and patients experienced fewer side effects.
The recommended dose for preventing flares of gout in individuals older than 16 years of age is 0.6 mg once or twice daily.
The recommended doses of colchicine for FMF are Children 4-6 years old: 0.3 to 1.8 mg daily Children 6-12 years old: 0.6 to 1.8 mg daily Adults and adolescents older than 12 years: 1.2 to 2.4 mg daily.
Total daily doses may be administered in two divided doses. Doses should be increased by 0.3 mg daily as tolerated until symptoms are controlled or maximum daily doses are reached. Doses should be decreased by 0.3 mg daily if side effects occur.
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