Smoking and tobacco use carry high risks to human health. In the UK, 12 million adults smoke (28% of men and 24% of women). Smoking is responsible for 114,000 deaths each year which represents one in every five deaths in the UK. Most of these deaths are from lung cancer, coronary heart disease and chronic obstructive lung disease, the main diseases associated with smoking. It is estimated that about half of all smokers will eventually be killed by their habit. This article covers the different options available to help quit smoking.